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Entropic Stabilization of Proteins by TMAO
The osmolyte trimethylamine N-oxide (TMAO) accumulates in the cell in response to osmotic stress and increases the thermodynamic stability of folded proteins. To understand the mechanism of TMAO induced stabilization of folded protein states, we systematically investigated the action of TMAO on seve...
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| Publié dans: | J Phys Chem B |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5260340/ https://ncbi.nlm.nih.gov/pubmed/21985427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp207289b |
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