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Subtype-specific CpG island shore methylation and mutation patterns in 30 breast cancer cell lines
BACKGROUND: Aberrant epigenetic modifications, including DNA methylation, are key regulators of gene activity in tumorigenesis. Breast cancer is a heterogeneous disease, and large-scale analyses indicate that tumor from normal and benign tissues, as well as molecular subtypes of breast cancer, can b...
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Publicado no: | BMC Syst Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5259919/ https://ncbi.nlm.nih.gov/pubmed/28155687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0356-2 |
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