ApoA-IV improves insulin sensitivity and glucose uptake in mouse adipocytes via PI3K-Akt Signaling

Insulin resistance is a risk factor for type 2 diabetes mellitus. We investigated the effect of ApoA-IV on glucose uptake in the adipose and muscle tissues of mice and cultured 3T3-L1 adipocytes. We found that treatment with ApoA-IV lowered fasting blood glucose in both WT and diabetic KKAy mice by...

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Vydáno v:Sci Rep
Hlavní autoři: Li, Xiaoming, Wang, Fei, Xu, Min, Howles, Philip, Tso, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259790/
https://ncbi.nlm.nih.gov/pubmed/28117404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41289
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