Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice

It is well known that insulin can activate both PI3K/Akt pathway, which is responsible for glucose uptake, and MAPK pathway, which is crucial for insulin resistance formation. But, it is unclear exactly how the two pathways coordinate to regulate insulin sensitivity upon hyperinsulinism stress of ty...

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מידע ביבליוגרפי
Main Authors: Yu, Xiao, Shen, Ning, Zhang, Ming-Liang, Pan, Fei-Yan, Wang, Chen, Jia, Wei-Ping, Liu, Chang, Gao, Qian, Gao, Xiang, Xue, Bin, Li, Chao-Jun
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2011
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173797/
https://ncbi.nlm.nih.gov/pubmed/21829168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.277
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