The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression

Most of what we know about gene transcription comes from the view of cells as molecular machines: focusing on the role of molecular modifications to the proteins carrying out transcriptional reactions at a loci-by-loci basis. This view ignores a critical reality: biological reactions do not happen i...

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Pubblicato in:Sci Rep
Autori principali: Almassalha, L. M., Tiwari, A., Ruhoff, P. T., Stypula-Cyrus, Y., Cherkezyan, L., Matsuda, H., Dela Cruz, M. A., Chandler, J. E., White, C., Maneval, C., Subramanian, H., Szleifer, I., Roy, H. K., Backman, V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259786/
https://ncbi.nlm.nih.gov/pubmed/28117353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41061
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