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HDAC Up-Regulation in Early Colon Field Carcinogenesis Is Involved in Cell Tumorigenicity through Regulation of Chromatin Structure

Normal cell function is dependent on the proper maintenance of chromatin structure. Regulation of chromatin structure is controlled by histone modifications that directly influence chromatin architecture and genome function. Specifically, the histone deacetylase (HDAC) family of proteins modulate ch...

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Detalhes bibliográficos
Main Authors: Stypula-Cyrus, Yolanda, Damania, Dhwanil, Kunte, Dhananjay P., Cruz, Mart Dela, Subramanian, Hariharan, Roy, Hemant K., Backman, Vadim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665824/
https://ncbi.nlm.nih.gov/pubmed/23724067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064600
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