Nanoscale changes in chromatin organization represent the initial steps of tumorigenesis: a transmission electron microscopy study

BACKGROUND: Nuclear alterations are a well-known manifestation of cancer. However, little is known about the early, microscopically-undetectable stages of malignant transformation. Based on the phenomenon of field cancerization, the tissue in the field of a tumor can be used to identify and study th...

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Autores principales: Cherkezyan, Lusik, Stypula-Cyrus, Yolanda, Subramanian, Hariharan, White, Craig, Dela Cruz, Mart, Wali, Ramesh K, Goldberg, Michael J, Bianchi, Laura K, Roy, Hemant K, Backman, Vadim
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995586/
https://ncbi.nlm.nih.gov/pubmed/24629088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-189
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