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The molecular pathogenesis of schwannomatosis, a paradigm for the co-involvement of multiple tumour suppressor genes in tumorigenesis

Schwannomatosis is characterized by the predisposition to develop multiple schwannomas and, less commonly, meningiomas. Despite the clinical overlap with neurofibromatosis type 2 (NF2), schwannomatosis is not caused by germline NF2 gene mutations. Instead, germline mutations of either the SMARCB1 or...

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Publicat a:Hum Genet
Autors principals: Kehrer-Sawatzki, Hildegard, Farschtschi, Said, Mautner, Victor-Felix, Cooper, David N.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258795/
https://ncbi.nlm.nih.gov/pubmed/27921248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1753-8
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