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Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins

Genetic and environmental factors contribute to age-dependent susceptibility to type 2 diabetes. Recent studies have reported reduced expression of PPARγ coactivator 1α (PGC-1α) and PGC-1β genes in skeletal muscle from type 2 diabetic patients, but it is not known whether this is an inherited or acq...

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Hlavní autoři: Ling, Charlotte, Poulsen, Pernille, Carlsson, Emma, Ridderstråle, Martin, Almgren, Peter, Wojtaszewski, Jørgen, Beck-Nielsen, Henning, Groop, Leif, Vaag, Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC525741/
https://ncbi.nlm.nih.gov/pubmed/15546003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421889
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