Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

OBJECTIVE: Common variants in FTO (the fat mass– and obesity-associated gene) associate with obesity and type 2 diabetes. The regulation and biological function of FTO mRNA expression in target tissue is unknown. We investigated the genetic and nongenetic regulation of FTO mRNA in skeletal muscle an...

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Main Authors: Grunnet, Louise G., Nilsson, Emma, Ling, Charlotte, Hansen, Torben, Pedersen, Oluf, Groop, Leif, Vaag, Allan, Poulsen, Pernille
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2009
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750213/
https://ncbi.nlm.nih.gov/pubmed/19587359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0205
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