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The Influenza M2 Ectodomain Regulates the Conformational Equilibria of the Transmembrane Proton Channel: Insights from Solid-State NMR

The influenza M2 protein is the target of the amantadine family of antiviral drugs, and its transmembrane (TM) domain structure and dynamics have been extensively studied. However, little is known about the structure of the highly conserved N-terminal ectodomain, which contains epitopes targeted by...

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Vydáno v:Biochemistry
Hlavní autoři: Kwon, Byungsu, Hong, Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5257201/
https://ncbi.nlm.nih.gov/pubmed/27571210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00727
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