The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest tumors worldwide. Understanding the function of gene expression alterations is a prerequisite for developing new strategies in diagnostic and therapy. GPRC5A (RAI3), coding for a seven transmembrane G protein-coupled receptor is known t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jahny, Elisabeth, Yang, Hai, Liu, Bin, Jahnke, Beatrix, Lademann, Franziska, Knösel, Thomas, Rümmele, Petra, Grützmann, Robert, Aust, Daniela E., Pilarsky, Christian, Denz, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256936/
https://ncbi.nlm.nih.gov/pubmed/28114355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170390
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