The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest tumors worldwide. Understanding the function of gene expression alterations is a prerequisite for developing new strategies in diagnostic and therapy. GPRC5A (RAI3), coding for a seven transmembrane G protein-coupled receptor is known t...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Jahny, Elisabeth, Yang, Hai, Liu, Bin, Jahnke, Beatrix, Lademann, Franziska, Knösel, Thomas, Rümmele, Petra, Grützmann, Robert, Aust, Daniela E., Pilarsky, Christian, Denz, Axel
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256936/
https://ncbi.nlm.nih.gov/pubmed/28114355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170390
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