The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest tumors worldwide. Understanding the function of gene expression alterations is a prerequisite for developing new strategies in diagnostic and therapy. GPRC5A (RAI3), coding for a seven transmembrane G protein-coupled receptor is known t...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Jahny, Elisabeth, Yang, Hai, Liu, Bin, Jahnke, Beatrix, Lademann, Franziska, Knösel, Thomas, Rümmele, Petra, Grützmann, Robert, Aust, Daniela E., Pilarsky, Christian, Denz, Axel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256936/
https://ncbi.nlm.nih.gov/pubmed/28114355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170390
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