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Serial segmental duplications during primate evolution result in complex human genome architecture
The human genome is particularly rich in low-copy repeats (LCRs) or segmental duplications (5%–10%), and this characteristic likely distinguishes us from lower mammals such as rodents. How and why the complex human genome architecture consisting of multiple LCRs has evolved remains an open question....
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC525679/ https://ncbi.nlm.nih.gov/pubmed/15520286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2746604 |
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