Phage display of ricin B chain and its single binding domains: system for screening galactose-binding mutants.
We demonstrate that the B chain of ricin toxin preserves its lectin activity when expressed as a fusion protein on the surface of fd phage. Moreover, B chain, which folds into two topologically similar globular domains, can be dissected into amino-terminal and carboxyl-terminal domains to form singl...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1992
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.9.3756 |
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