Phage display of ricin B chain and its single binding domains: system for screening galactose-binding mutants.

We demonstrate that the B chain of ricin toxin preserves its lectin activity when expressed as a fusion protein on the surface of fd phage. Moreover, B chain, which folds into two topologically similar globular domains, can be dissected into amino-terminal and carboxyl-terminal domains to form singl...

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Publikašuvnnas:	Proc Natl Acad Sci U S A
Váldodahkkit:	Swimmer, C, Lehar, S M, McCafferty, J, Chiswell, D J, Blättler, W A, Guild, B C
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	National Academy of Sciences 1992
Fáttát:	Research Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1373889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.9.3756
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