ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations

We investigated the proposal that ankylosing spondylitis (AS) is associated with unusual ERAP1 genotypes. ERAP1 haplotypes were constructed for 213 AS cases and 46 rheumatoid arthritis controls using family data. Haplotypes were generated from five common ERAP1 single nucleotide polymorphisms (SNPs)...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Roberts, Amity R., Appleton, Louise H., Cortes, Adrian, Vecellio, Matteo, Lau, Jonathan, Watts, Laura, Brown, Matthew A., Wordsworth, Paul
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5255627/
https://ncbi.nlm.nih.gov/pubmed/28049827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618856114
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