ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations

We investigated the proposal that ankylosing spondylitis (AS) is associated with unusual ERAP1 genotypes. ERAP1 haplotypes were constructed for 213 AS cases and 46 rheumatoid arthritis controls using family data. Haplotypes were generated from five common ERAP1 single nucleotide polymorphisms (SNPs)...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Roberts, Amity R., Appleton, Louise H., Cortes, Adrian, Vecellio, Matteo, Lau, Jonathan, Watts, Laura, Brown, Matthew A., Wordsworth, Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5255627/
https://ncbi.nlm.nih.gov/pubmed/28049827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618856114
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