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The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
The Ezh2 protein endows the Polycomb PRC2 and PRC3 complexes with histone lysine methyltransferase (HKMT) activity that is associated with transcriptional repression. We report that Ezh2 expression was developmentally regulated in the myotome compartment of mouse somites and that its down-regulation...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC525543/ https://ncbi.nlm.nih.gov/pubmed/15520282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1241904 |
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