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The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

The Ezh2 protein endows the Polycomb PRC2 and PRC3 complexes with histone lysine methyltransferase (HKMT) activity that is associated with transcriptional repression. We report that Ezh2 expression was developmentally regulated in the myotome compartment of mouse somites and that its down-regulation...

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Bibliographic Details
Main Authors: Caretti, Giuseppina, Di Padova, Monica, Micales, Bruce, Lyons, Gary E., Sartorelli, Vittorio
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC525543/
https://ncbi.nlm.nih.gov/pubmed/15520282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1241904
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