Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells

Satellite cells (SCs) sustain muscle growth and empower adult skeletal muscle with vigorous regenerative abilities. Here, we report that EZH2, the enzymatic subunit of the Polycomb-repressive complex 2 (PRC2), is expressed in both Pax7(+)/Myf5(−) stem cells and Pax7(+)/Myf5(+) committed myogenic pre...

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Detalhes bibliográficos
Main Authors: Juan, Aster H., Derfoul, Assia, Feng, Xuesong, Ryall, James G., Dell'Orso, Stefania, Pasut, Alessandra, Zare, Hossein, Simone, James M., Rudnicki, Michael A., Sartorelli, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078704/
https://ncbi.nlm.nih.gov/pubmed/21498568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2027911
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