Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function

Alveolar rhabdomyosarcoma is an aggressive childhood muscle cancer for which outcomes are poor when the disease is advanced. Although well-developed mouse models exist for embryonal and pleomorphic rhabdomyosarcomas, neither a spontaneous nor a transgenic mouse model of alveolar rhabdomyosarcoma has...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Keller, Charles, Arenkiel, Benjamin R., Coffin, Cheryl M., El-Bardeesy, Nabeel, DePinho, Ronald A., Capecchi, Mario R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15489287/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1244004
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