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Xenopus Cds1 Is Regulated by DNA-Dependent Protein Kinase and ATR during the Cell Cycle Checkpoint Response to Double-Stranded DNA Ends

The checkpoint kinase Cds1 (Chk2) plays a key role in cell cycle checkpoint responses with functions in cell cycle arrest, DNA repair, and induction of apoptosis. Proper regulation of Cds1 is essential for appropriate cellular responses to checkpoint-inducing insults. While the kinase ATM has been s...

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Detalhes bibliográficos
Main Authors: McSherry, Troy D., Mueller, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525475/
https://ncbi.nlm.nih.gov/pubmed/15509799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.22.9968-9985.2004
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