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Highly Active Anti-Pneumocystis carinii Compounds in a Library of Novel Piperazine-Linked Bisbenzamidines and Related Compounds

Trimethoprim-sulfamethoxazole and pentamidine isethionate have been used extensively for the prophylaxis and therapy of pneumonia caused by Pneumocystis jirovecii. Problems associated with toxicity and potential emerging resistance for both therapies necessitate the development of safe and effective...

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Hlavní autoři: Cushion, Melanie T., Walzer, Peter D., Collins, Margaret S., Rebholz, Sandra, Vanden Eynde, Jean Jacques, Mayence, Annie, Huang, Tien L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC525440/
https://ncbi.nlm.nih.gov/pubmed/15504843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4209-4216.2004
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