In Vitro Evolution of Itraconazole Resistance in Aspergillus fumigatus Involves Multiple Mechanisms of Resistance

We investigated the evolution of resistance to the antifungal drug itraconazole in replicate populations of Aspergillus fumigatus that were founded from a strain with a genotype of sensitivity to a single drug and then propagated under uniform conditions. For each population, conidia were serially t...

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Hlavní autoři: da Silva Ferreira, Márcia Eliana, Capellaro, José Luiz, dos Reis Marques, Everaldo, Malavazi, Iran, Perlin, David, Park, Steven, Anderson, James B., Colombo, Arnaldo L., Arthington-Skaggs, Beth A., Goldman, Maria Helena S., Goldman, Gustavo H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC525395/
https://ncbi.nlm.nih.gov/pubmed/15504870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4405-4413.2004
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