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Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling

The unfolding of apoptosis involves the cleavage of hundreds of proteins by the caspase family of cysteinyl peptidases. Among those substrates are proteins involved in intracellular vesicle trafficking with a net outcome of shutting down the crucial processes governing protein transport to organelle...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Duclos, Catherine M, Champagne, Audrey, Carrier, Julie C, Saucier, Caroline, Lavoie, Christine L, Denault, Jean-Bernard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253419/
https://ncbi.nlm.nih.gov/pubmed/28179995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.100
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