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Engineered Liver Platforms for Different Phases of Drug Development

Drug-induced liver injury (DILI) remains a leading cause of drug withdrawal from human clinical trials or the marketplace. Due to species-specific differences in liver pathways, predicting human-relevant DILI using in vitro human liver models is critical. Microfabrication tools allow precise control...

詳細記述

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書誌詳細
出版年:Trends Biotechnol
主要な著者: Ware, Brenton R., Khetani, Salman R.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253249/
https://ncbi.nlm.nih.gov/pubmed/27592803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2016.08.001
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