Selection of Single-Chain Antibodies against the VP8* Subunit of Rotavirus VP4 Outer Capsid Protein and Their Expression in Lactobacillus casei

Single-chain antibodies (scFv) recognizing the VP8* fraction of rotavirus outer capsid and blocking rotavirus infection in vitro were isolated by phage display. Vectors for the extracellular expression in Lactobacillus casei of one of the scFv were constructed. L. casei was able to secrete active sc...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Appl Environ Microbiol
Hauptverfasser:	Monedero, Vicente, Rodríguez-Díaz, Jesús, Viana, Rosa, Buesa, Javier, Pérez-Martínez, Gaspar
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Physiology and Biotechnology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525132/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15528568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.11.6936-6939.2004
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!