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Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling

Nicousamide, a clinical phase II renal protective new drug, has been demonstrated to have renal protective effect on diabetic nephropathy (DN) by experimental animal model. Its known molecular mechanisms include AGE formation blocking and moderately decreasing the blood pressure. Nicousamide shows p...

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Podrobná bibliografie
Vydáno v:Am J Transl Res
Hlavní autoři: Zhang, Sen, Wang, Dongjie, Xue, Nina, Lai, Fangfang, Ji, Ming, Jin, Jing, Chen, Xiaoguang
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250708/
https://ncbi.nlm.nih.gov/pubmed/28123638
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