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Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling

Nicousamide, a clinical phase II renal protective new drug, has been demonstrated to have renal protective effect on diabetic nephropathy (DN) by experimental animal model. Its known molecular mechanisms include AGE formation blocking and moderately decreasing the blood pressure. Nicousamide shows p...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhang, Sen, Wang, Dongjie, Xue, Nina, Lai, Fangfang, Ji, Ming, Jin, Jing, Chen, Xiaoguang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250708/
https://ncbi.nlm.nih.gov/pubmed/28123638
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