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Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling

Nicousamide, a clinical phase II renal protective new drug, has been demonstrated to have renal protective effect on diabetic nephropathy (DN) by experimental animal model. Its known molecular mechanisms include AGE formation blocking and moderately decreasing the blood pressure. Nicousamide shows p...

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Dades bibliogràfiques
Publicat a:Am J Transl Res
Autors principals: Zhang, Sen, Wang, Dongjie, Xue, Nina, Lai, Fangfang, Ji, Ming, Jin, Jing, Chen, Xiaoguang
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250708/
https://ncbi.nlm.nih.gov/pubmed/28123638
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