Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy

The activation of the highly conserved unfolded protein response (UPR) is prominent in the pathogenesis of the most prevalent neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS), which are classically characterized by an acc...

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Vydáno v:Acta Neuropathol
Hlavní autoři: Launay, Nathalie, Ruiz, Montserrat, Grau, Laia, Ortega, Francisco J., Ilieva, Ekaterina V., Martínez, Juan José, Galea, Elena, Ferrer, Isidre, Knecht, Erwin, Pujol, Aurora, Fourcade, Stéphane
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2016
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250669/
https://ncbi.nlm.nih.gov/pubmed/28004277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1655-9
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