Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy

The activation of the highly conserved unfolded protein response (UPR) is prominent in the pathogenesis of the most prevalent neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS), which are classically characterized by an acc...

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書目詳細資料
發表在:Acta Neuropathol
Main Authors: Launay, Nathalie, Ruiz, Montserrat, Grau, Laia, Ortega, Francisco J., Ilieva, Ekaterina V., Martínez, Juan José, Galea, Elena, Ferrer, Isidre, Knecht, Erwin, Pujol, Aurora, Fourcade, Stéphane
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2016
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Original Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250669/
https://ncbi.nlm.nih.gov/pubmed/28004277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1655-9
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