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Upon Accounting for the Impact of Isoenzyme Loss, Gene Deletion Costs Anticorrelate with Their Evolutionary Rates

System-level metabolic network models enable the computation of growth and metabolic phenotypes from an organism’s genome. In particular, flux balance approaches have been used to estimate the contribution of individual metabolic genes to organismal fitness, offering the opportunity to test whether...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Jacobs, Christopher, Lambourne, Luke, Xia, Yu, Segrè, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249160/
https://ncbi.nlm.nih.gov/pubmed/28107392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170164
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