Loss of Ability To Self-Heal Malaria upon Taurine Transporter Deletion

Deletion of the taurine transporter gene (taut) results in lowered levels of taurine, the most abundant amino acid in mammals. Here, we show that taut(−)(/)(−) mice have lost their ability to self-heal blood-stage infections with Plasmodium chabaudi malaria. All taut(−)(/)(−) mice succumb to infecti...

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Autori principali: Delić, Denis, Warskulat, Ulrich, Borsch, Elena, Al-Qahtani, Saad, Al-Quraishi, Saleh, Häussinger, Dieter, Wunderlich, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849432/
https://ncbi.nlm.nih.gov/pubmed/20100858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01159-09
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