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Upon Accounting for the Impact of Isoenzyme Loss, Gene Deletion Costs Anticorrelate with Their Evolutionary Rates

System-level metabolic network models enable the computation of growth and metabolic phenotypes from an organism’s genome. In particular, flux balance approaches have been used to estimate the contribution of individual metabolic genes to organismal fitness, offering the opportunity to test whether...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Jacobs, Christopher, Lambourne, Luke, Xia, Yu, Segrè, Daniel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249160/
https://ncbi.nlm.nih.gov/pubmed/28107392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170164
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