2-O, 3-O Desulfated Heparin Blocks High Mobility Group Box 1 Release by Inhibition of p300 Acetyltransferase Activity

High mobility group box 1 (HMGB1) is an alarmin released from macrophages after infection or inflammation and is a biomarker of lung disease progression in patients with cystic fibrosis. We reported that 2-O, 3-O desulfated heparin (ODSH) inhibits the release of HMGB1 from murine macrophages trigger...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Respir Cell Mol Biol
Egile Nagusiak: Zheng, Shuo, Kummarapurugu, Apparao B., Afosah, Daniel K., Sankaranarayanan, Nehru Viji, Boothello, Rio S., Desai, Umesh R., Kennedy, Thomas, Voynow, Judith A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Thoracic Society 2017
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248960/
https://ncbi.nlm.nih.gov/pubmed/27585400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0069OC
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak