Combinatorial virtual library screening analysis of antithrombin binding oligosaccharide motif generation by heparan sulfate 3-O-Sulfotransferase 1()

Pharmaceutical heparin’s activity arises from a key high affinity and high selectivity antithrombin binding motif, which forms the basis for its use as an anticoagulant. The current problems with the supply of pig heparin raises the emphasis of understanding heparin biosynthesis so as to control and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Comput Struct Biotechnol J
Egile Nagusiak: Sankaranarayanan, Nehru Viji, Bi, Yiling, Kuberan, Balagurunathan, Desai, Umesh R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Research Network of Computational and Structural Biotechnology 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183009/
https://ncbi.nlm.nih.gov/pubmed/32346466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.03.008
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