Combinatorial virtual library screening analysis of antithrombin binding oligosaccharide motif generation by heparan sulfate 3-O-Sulfotransferase 1()

Pharmaceutical heparin’s activity arises from a key high affinity and high selectivity antithrombin binding motif, which forms the basis for its use as an anticoagulant. The current problems with the supply of pig heparin raises the emphasis of understanding heparin biosynthesis so as to control and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Comput Struct Biotechnol J
Prif Awduron: Sankaranarayanan, Nehru Viji, Bi, Yiling, Kuberan, Balagurunathan, Desai, Umesh R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Research Network of Computational and Structural Biotechnology 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183009/
https://ncbi.nlm.nih.gov/pubmed/32346466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.03.008
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