Unique and Redundant Functions of p70 Ribosomal S6 Kinase Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis

The p70 ribosomal S6 kinase (p70S6K) is a downstream substrate that is phosphorylated and activated by the mammalian target of rapamycin complex and regulates multiple cellular processes associated with pulmonary fibrogenesis. Two isoforms of the p70S6K have been identified (S6K1 and S6K2), but thei...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Am J Respir Cell Mol Biol
Autores principales: Madala, Satish K., Sontake, Vishwaraj, Edukulla, Ramakrishna, Davidson, Cynthia R., Schmidt, Stephanie, Hardie, William D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2016
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248954/
https://ncbi.nlm.nih.gov/pubmed/27438654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0090OC
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares