Protein Kinase Cζ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury

Protein kinase Cζ (PKCζ) is highly expressed in the lung, where it plays several regulating roles in the pathogenesis of acute lung injury (ALI). Proliferation and differentiation of integrin β4(+) distal lung epithelial progenitor cells seem to play a key role in proper lung regeneration. We invest...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Buonfiglio, Luis G. Vargas, Bagegni, Mosaab, Borcherding, Jennifer A., Sieren, Jessica C., Caraballo, Juan C., Reger, Andrew, Zabner, Joseph, Li, Xiaopeng, Comellas, Alejandro P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248948/
https://ncbi.nlm.nih.gov/pubmed/27486964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0006OC
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