Protein Kinase Cζ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury

Protein kinase Cζ (PKCζ) is highly expressed in the lung, where it plays several regulating roles in the pathogenesis of acute lung injury (ALI). Proliferation and differentiation of integrin β4(+) distal lung epithelial progenitor cells seem to play a key role in proper lung regeneration. We invest...

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Detalles Bibliográficos
Publicado en:Am J Respir Cell Mol Biol
Main Authors: Buonfiglio, Luis G. Vargas, Bagegni, Mosaab, Borcherding, Jennifer A., Sieren, Jessica C., Caraballo, Juan C., Reger, Andrew, Zabner, Joseph, Li, Xiaopeng, Comellas, Alejandro P.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2016
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248948/
https://ncbi.nlm.nih.gov/pubmed/27486964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0006OC
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