Protein Kinase Cζ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury

Protein kinase Cζ (PKCζ) is highly expressed in the lung, where it plays several regulating roles in the pathogenesis of acute lung injury (ALI). Proliferation and differentiation of integrin β4(+) distal lung epithelial progenitor cells seem to play a key role in proper lung regeneration. We invest...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Buonfiglio, Luis G. Vargas, Bagegni, Mosaab, Borcherding, Jennifer A., Sieren, Jessica C., Caraballo, Juan C., Reger, Andrew, Zabner, Joseph, Li, Xiaopeng, Comellas, Alejandro P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248948/
https://ncbi.nlm.nih.gov/pubmed/27486964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0006OC
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