Cell Type-specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex

Alternative splicing is prevalent in the mammalian brain. To interrogate the functional role of alternative splicing in neural development, we analyzed purified neural progenitor cells (NPCs) and neurons from developing cerebral cortices, revealing hundreds of differentially spliced exons that prefe...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Zhang, Xiaochang, Chen, Ming Hui, Wu, Xuebing, Kodani, Andrew, Fan, Jean, Doan, Ryan, Ozawa, Manabu, Ma, Jacqueline, Yoshida, Nobuaki, Reiter, Jeremy F., Black, Douglas L., Kharchenko, Peter V., Sharp, Phillip A., Walsh, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248659/
https://ncbi.nlm.nih.gov/pubmed/27565344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.025
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