Cell Type-specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex

Alternative splicing is prevalent in the mammalian brain. To interrogate the functional role of alternative splicing in neural development, we analyzed purified neural progenitor cells (NPCs) and neurons from developing cerebral cortices, revealing hundreds of differentially spliced exons that prefe...

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Publicat a:Cell
Autors principals: Zhang, Xiaochang, Chen, Ming Hui, Wu, Xuebing, Kodani, Andrew, Fan, Jean, Doan, Ryan, Ozawa, Manabu, Ma, Jacqueline, Yoshida, Nobuaki, Reiter, Jeremy F., Black, Douglas L., Kharchenko, Peter V., Sharp, Phillip A., Walsh, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248659/
https://ncbi.nlm.nih.gov/pubmed/27565344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.025
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