ロード中...
PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers
The spleen tyrosine kinase (SYK) regulates immune cell activation in response to engagement of a variety of receptors, making it an intriguing target for the treatment of inflammatory and autoimmune disorders as well as certain B‐cell malignancies. We have previously reported on the discovery and pr...
保存先:
| 出版年: | J Clin Pharmacol |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5248591/ https://ncbi.nlm.nih.gov/pubmed/27406873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.794 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|