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Crystal structure of 4-hydroxybutyryl-CoA dehydratase: Radical catalysis involving a [4Fe–4S] cluster and flavin

Dehydratases catalyze the breakage of a carbon—oxygen bond leading to unsaturated products via the elimination of water. The 1.6-Å resolution crystal structure of 4-hydroxybutyryl-CoA dehydratase from the γ-aminobutyrate-fermenting Clostridium aminobutyricum represents a new class of dehydratases wi...

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Detalhes bibliográficos
Main Authors: Martins, Berta M., Dobbek, Holger, Çinkaya, Irfan, Buckel, Wolfgang, Messerschmidt, Albrecht
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524839/
https://ncbi.nlm.nih.gov/pubmed/15496473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403952101
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