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Substrate-Induced Radical Formation in 4-Hydroxybutyryl Coenzyme A Dehydratase from Clostridium aminobutyricum

4-Hydroxybutyryl-coenzyme A (CoA) dehydratase (4HBD) from Clostridium aminobutyricum catalyzes the reversible dehydration of 4-hydroxybutyryl-CoA to crotonyl-CoA and the irreversible isomerization of vinylacetyl-CoA to crotonyl-CoA. 4HBD is an oxygen-sensitive homotetrameric enzyme with one [4Fe-4S]...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Zhang, Jin, Friedrich, Peter, Pierik, Antonio J., Martins, Berta M., Buckel, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292473/
https://ncbi.nlm.nih.gov/pubmed/25452282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03099-14
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