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AcsF Catalyzes the ATP-dependent Insertion of Nickel into the Ni,Ni-[4Fe4S] Cluster of Acetyl-CoA Synthase

Acetyl-CoA synthase (ACS) catalyzes the reversible condensation of CO, CoA, and a methyl-cation to form acetyl-CoA at a unique Ni,Ni-[4Fe4S] cluster (the A-cluster). However, it was unknown which proteins support the assembly of the A-cluster. We analyzed the product of a gene from the cluster conta...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gregg, Christina M., Goetzl, Sebastian, Jeoung, Jae-Hun, Dobbek, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000062/
https://ncbi.nlm.nih.gov/pubmed/27382049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731638
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