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Susceptibility to Apoptosis in Insulin-like Growth Factor-I Receptor-deficient Brown Adipocytes

Fetal brown adipocytes are insulin-like growth factor-I (IGF-I) target cells. To assess the importance of the IGF-I receptor (IGF-IR) in brown adipocytes during fetal life, we have generated immortalized brown adipocyte cell lines from the IGF-IR(-/-) mice. Using this experimental model, we demonstr...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Valverde, Angela M., Mur, Cecilia, Brownlee, Michael, Benito, Manuel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC524782/
https://ncbi.nlm.nih.gov/pubmed/15356271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0853
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