Fulminant Myocarditis with Combination Immune Checkpoint Blockade

Immune checkpoint inhibitors significantly improve clinical outcomes in numerous malignancies, but high-grade immune-related adverse events can occur, particularly with combination immunotherapy. Herein, we report two melanoma patients who developed fatal myocarditis following treatment with ipilimu...

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Bibliografske podrobnosti
izdano v:N Engl J Med
Main Authors: Johnson, Douglas B., Balko, Justin M., Compton, Margaret L., Chalkias, Spyridon, Gorham, Joshua, Xu, Yaomin, Hicks, Mellissa, Puzanov, Igor, Alexander, Matthew R., Bloomer, Tyler L., Becker, Jason, Slosky, David A., Phillips, Elizabeth J., Pilkinton, Mark A., Craig-Owens, Laura, Kola, Nina, Plautz, Gregory, Reshef, Daniel S., Deutsch, Jonathan S., Deering, Raquel P., Olenchock, Benjamin A., Lichtman, Andrew H., Roden, Dan M., Seidman, Christine E., Koralnik, Igor J., Seidman, Jonathan G., Hoffman, Robert D., Taube, Janis M., Diaz, Luis A., Anders, Robert A., Sosman, Jeffrey A., Moslehi, Javid J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247797/
https://ncbi.nlm.nih.gov/pubmed/27806233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1609214
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